Factsheet Key Facts Lassa fever is an acute viral haemorrhagic illness of days duration that occurs in West Africa. The Lassa virus is transmitted to humans via contact with food or household items contaminated with rodent urine or faeces.
Lassa fever Introduction This paper discusses Lassa fever, an infectious disease with regard to its causality organism, transmission, epidemiology, and factors causing the illness, clinical manifestation and diagnosis and the role of the nurse in controlling the illness.
Lassa fever is a severe viral hemorrhagic infection caused by Lassa virus, which is affiliated to arenavidae virus family. West African communities from countries such as Nigeria, Ghana, Guinea, and Liberia among others have registered high prevalence rates of the infection typified by approximately thousand cases and deaths annually.
The virus is enveloped, mono-stranded, and double-segmented having Ribonucleic Acid as genetic material. The virus might display various dissimilar shapes hence varied pleomorphism characteristics measuring approximately 80 to nanometer in thickness. The viral envelope or covering is studded with glycoproteins comprising of tetrameric composites that belong to viral glycoproteins GP1 and GP2.
The virus has the capability of managing its replication process rapidly, which is two-step progression. The initial step is the transcription of mRNA copies to minus-sense genome. This process is essential to the virus since it guarantees sufficient provision of viral proteins for the forthcoming replication step, which involves transformation of proteins N and L from the mRNA Dworkin, The above two processes reveal the control of the virus over its replication process, hence not easily recognized in the host immune system.
Nucleotide research on the virus has revealed that Lassa virus contains four lineages recognized in Nigeria, Guinea, Liberia, and Sierra Leone. The receptor is flexible and is composed of the proteins of the extracellular matrix.
The flexibility of the receptor is extended to its usage by the prototypic arenavirus lymphocytic choriomeningitis virus. Lassa virus uses an endocrytic pathway that lacks clathrin, caveolin, dynamin, and actin unlike other enveloped viruses.
The virus carries a speedy delivery of endosomes once in the host cell through vesicular. The modes of transmission of the infection to human beings exist in different forms. The two modes are natural reservoir and vectors.
The multimammate rat scientifically referred to as mastomys natalensis is the natural reservoir of Lassa virus, which causes Lassa fever. The precise species of the rodent associated with disease has not yet been discovered, but it is largely believed that species natalensis is responsible for fever.
The distribution of the virus depends on various reasons. Rodents are present inside houses where people live and some of these rodents are the reservoir of the Lassa virus Georgiev, The multimammate rat breeds regularly, infecting their progeny with during birth. The resultant effect is long chain of the viral infection to host and host to people.
The transmission is considered zoonotic since it spreads from rats to humans. Rats have an asymptomatic state of the virus, which is the reason why they can survive without being affected. Aerolization of the feces and urine makes the viral tiny particles vulnerable inhalation by human beings.
However, injured skins or mucous membranes expose the body fluid infective substances. Some propositions also exist advocating that the disease can be transmitted through sexual intercourse.
Research reveals that building materials used by the community uses materials such as woods and mud in construction. However, some concrete building also exists. Mud walls with holes provided habitat for the rodent carrying the virus.
Lower parts of West Africa have some dense vegetation, which also provide habitat. These countries are characterized by constant outbreaks of the illness. Notably, the endemicity of the Lassa fever is not restricted to political borders but instead by geographical areas.Port Manteaux churns out silly new words when you feed it an idea or two.
Enter a word (or two) above and you'll get back a bunch of portmanteaux created by jamming together words that are conceptually related to your inputs.. For example, enter "giraffe" and you'll get . Mar 11, · Lassa fever is a sudden onset viral illness that occurs in West Africa.
The virus is transmitted to humans via objects and food contaminated with the virus, or direct contact with the feces and urine of an infected rat. It can also be transmitted person-to-person through contact with secretions and excretions of someone who is infected%().
Nov 29, · Vaccine. Production of a combined, single dose vaccine against yellow fever and Lassa fever has been proposed. 25 The cost and logistical problems of delivering it would be huge, particularly since fewer than 20% of districts in the countries studied achieve 80% uptake of childhood pfmlures.com by: Since , the independent Kingdom of Talossa has thrived on the shore of Lake Michigan.
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Next time, try using the search term “Lassa fever cases out of danger crossword” or “Lassa fever cases out of danger crossword clue” when searching for help with your puzzle on the web. This was the consensus of participants at a one-day sensitisation meeting with farmers and other stakeholders on Lassa fever on Tuesday in Akure.
The meeting, which was organised by the department of Veterinary Disease and Pest Control of the Federal Ministry of Agriculture, was declared open by the Ondo State Commissioner for Agriculture, Chief Adegboyega [ ]Author: Ohams.